The type and amount of matrix proteins synthesized by human tumor cells in vitro appears to parallel that of cultured normal cell counterparts to some extent. We have broadened these observations to a variety of human tumors to determine whether these patterns might allow more precise catergorization of the tumor's origins. In addition, we are characterizing a new matrix protein sythesized by some of these tumors. The identity, function, and molecular organization within the extracellular matrix of this component is currently unknown.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Biology And Diagnosis (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CB000545-07
Application #
4691695
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Cancer Biology and Diagnosis
Department
Type
DUNS #
City
State
Country
United States
Zip Code