This project is designed to evaluate the nature of lactogenic hormone receptors and the factors (including other hormones) which affect binding of the hormone to this molecule. Studies include 1) purification of the receptor from human tissue and preparation and characterization of an antibody against it; 2) examination of the nature of the subunits of the receptor, 3) characterization of the nature of the interaction of Tamoxifen with membrane bound receptors related to the lactogen receptor, and 4) define the relationship of monoclonal antibody B6.2 to human lactogenic hormone receptors.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Biology And Diagnosis (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CB008274-07
Application #
3939280
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Cancer Biology and Diagnosis
Department
Type
DUNS #
City
State
Country
United States
Zip Code