Statistically derived Phi-psi maps for each type of residue indicate substantial improvements in X-ray data over previous tabulations. Position effects in regular secondary regions show strong effects for some types of residues, especially proline, aromatic and polar groups. A simple dipolar solvent model indicates an asymmetry to electrostatic interactions. Favorable interactions appear to be enhanced and extended to longer range. Meaningful homologies were demonstrated between ceruloplasmin and two blood clotting proteins, Factor V and Factor VIII.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Biology And Diagnosis (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CB008320-10
Application #
4691831
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Cancer Biology and Diagnosis
Department
Type
DUNS #
City
State
Country
United States
Zip Code