Monoclonal antibodies (MAbs) have been utilized with immunohistochemical methods for the (a) detection of occult carcinoma in surgical and cytology preparations, (b) phenotyping of malignant cell populations, (c) differentiation of histologic tumor types, and (d) identification of various cellular products. MAbs with selective reactivity against tumor associated antigens have specifically been adapted for use with cytologic preparations including cytospins, membranes, and fine needle aspiration biopsies for the detection and differentiation of carcinomas from benign cell types and other cancerous lesions.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Biology And Diagnosis (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CB009012-03
Application #
3963058
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Cancer Biology and Diagnosis
Department
Type
DUNS #
City
State
Country
United States
Zip Code