A new method for measuring myocardial thickening from gated PET or SPECT scans is being developed. This method combines the best features of the so called """"""""geometric"""""""" methods with those of the """"""""counts based"""""""" methods. The method has been tested with theoretical models, with gated cardiac magnetic resonance based simulated images, and with phantom measurements. The method is found to be more linear and more immune to noise than other previously reported methods. Preliminary patient studies indicate a statistically significant improvement in categorizing subjects with wall thickening abnormalities. Further work will center on clinical applications of the technique. A description and validation of the technique was presented orally and in abstract form, and is now being submitted for publication as a full article.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL000411-01
Application #
5201117
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code