We will test five normal volunteers before and serially after anesthesia of the median, radial, and ulnar nerves at the forearm. Noninvasive magnetic stimulation will be delivered over different scalp positions. If we detect enlargement of the alpha motoneuron pool recruited and the motor representation areas for muscles immediately proximal to the level of anesthesia (biceps, deltoid), it would indicate unmasking of preexistent connections, since no new synapses can be established in such a short time. This would provide valuable information on the mechanisms of reorganization of human central nervous system following deafferentation.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL008032-01
Application #
3874328
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code