B hominis mitochondria have no lactic dehydrogenase, isocitrate dehydrogenase, glycerol dehydrogenase, cytochrome C oxidase, glutamate dehydrogenase, dihydrolipoemide dehydrogenase, alpha keto-glutarate dehydrogenase, or pyruvate dehydrogenase enzymatic activity. B hominis has an absolute requirement for cholesterol. The main acid products from glucose are acetic, propionic, succinic, lactic, and isovaleric acids. Spectrographic analysis for cytochromes and flavoprotein was negative. Thus, these mitochondria lack enzymes, as well as cytochromes that are normally present in mitochondria.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL010009-16
Application #
3874332
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
16
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code