Abstract

A more versatile cyanoethyl-protected phosyphoramidite reagent for the synthesis of oligonucleotides that contain dihydro-5-aza-cytosine instead of cytosine was developed. Its efficiency in automated DNA synthesis is being evaluated with biologically selected target 24-mers.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CM006175-07
Application #
3838036
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Division of Cancer Treatment
Department
Type
DUNS #
City
State
Country
United States
Zip Code