A detailed study has been made previously of the dosimetry of total skin electron irradiation. This study has quantified and improved the whole skin treatments received by patients with mycosis fungoides (MF). The treatment technique has now been updated and implemented on the new Clinac 20 linear accelerator. A study has been started to selectively and locally modify the fluence rate to allow for the locally higher dose rates to the hands and feet, which now require cumbersome shielding over part of the treatment course. Total skin electron radiation is given routinely on the Clinac 20. The project directed at modification of electron fluence distribution by means of a grid technique has shown promising initial results. Practical application needs some further work. A paper is in preparation. In the meantime, the """"""""gloves-and-boots"""""""" (protection of hands and feet) have been made considerably less uncomfortable and more effective, improving the conditions for consistent treatment.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CM006333-08
Application #
3939514
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
8
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Cancer Treatment
Department
Type
DUNS #
City
State
Country
United States
Zip Code