Human herpesvirus 8 (HHV-8): An immunofluorescence assay for latent HHV-8 antibodies revealed that U.S. homosexual men experienced an HHV-8 epidemic concurrent with the HIV epidemic in the early 1980s. HHV-8 infection was associated with numerous homosexual partners, and 35% of subjects with both HHV-8 and HIV developed Kaposis sarcoma within 10 years. Human Papillomaviruses (HPV): Prevalence of antibodies to HPV 16 virus-like particles was increased in sexually transmitted disease clinic patients, especially among women. Polyomaviruses: A study to examine reproducibility in detection of SV40 DNA in human mesothelioma or normal lung in nine laboratories was initiated. Hepatitis Viruses: Among subjects in the Multicenter Hemophilia Cohort Study, hepatitis C virus (HCV) genotypes were found to change over time, especially with HIV co-infection, suggesting serial reactivation of latent HCV clones. - Human Subjects & Human Subjects: Minor under 18 Years Old & Human Subjects: Interview, Questionaires, or Surveys Only & Human Tissues, Fluids, Cells, etc.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CP005782-05
Application #
6289524
Study Section
Special Emphasis Panel (VEB)
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
United States
Zip Code
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