1. We completed analysis of the main case-control study and published approximately 50 reports in peer-reviewd journals. 2. We demonstrated that the patterns of risk vary according to the sub-type of lymphoma. 3. We showed that genetic risk factors for occurrance of NHL also predicted survival; We're continuing to explore other sub-types to compare the patterns of etilogy and survival. 4. To investigate the affective genetic polymorphism with more power, we pooled the data from two tother canse-control studies, one from Yale and one from New South Wales. 5. We continued to collaborate with InterLymph and we reported on the pooled estimates for overweight, sunlight, hepatitis C virus, hair dyes, and reproductive history. 6. We combined environmental data from other sources with study data to continue to investigate environmental risks. This work is ongoing.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CP010170-08
Application #
7733731
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
8
Fiscal Year
2008
Total Cost
$1,222,206
Indirect Cost
Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
United States
Zip Code
DellaValle, Curt T; Wheeler, David C; Deziel, Nicole C et al. (2013) Environmental determinants of polychlorinated biphenyl concentrations in residential carpet dust. Environ Sci Technol 47:10405-14
Zahm, Shelia Hoar; Morton, Lindsay M; Bernstein, Leslie et al. (2008) Re: Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma, author response. Carcinogenesis 29:1084-5
Hartge, Patricia; Colt, Joanne S; Severson, Richard K et al. (2005) Residential herbicide use and risk of non-Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev 14:934-7
Engels, Eric A; Chatterjee, Nilanjan; Cerhan, James R et al. (2004) Hepatitis C virus infection and non-Hodgkin lymphoma: results of the NCI-SEER multi-center case-control study. Int J Cancer 111:76-80
Colt, Joanne S; Lubin, Jay; Camann, David et al. (2004) Comparison of pesticide levels in carpet dust and self-reported pest treatment practices in four US sites. J Expo Anal Environ Epidemiol 14:74-83