We have been examining the glomerular lesions in kidneys from patients who undergo a nephrectomy for renal cancer. In areas non-invaded by the tumor there is in half the cases examined a marked mesangial proliferation and occasional synechiae suggesting a glomerular disease which could be mediated by growth factors released by the tumor.

Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
U.S. National Inst Diabetes/Digst/Kidney
Department
Type
DUNS #
City
State
Country
United States
Zip Code