Efficient synthesis of several N-protected 6-acetoxynortropin-3-ones has been achieved. N-Benzyl-6-acetoxynortropin-3-one was converted into 6- acetoxynortropane. Bromination of 6-acetoxytropin-3-one and its N- protected noranalogs afforded mixtures of 2- and 4-brominated ketones.

Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code