Methyl bromide (MB) was dissolved in peanut oil and given by gavage at 50 mg/kg body weight to Wistar rats five times per week for 13 to 25 weeks. At 25 weeks nearly 100% of the rats receiving MB had hyperplastic lesions of the forestomach which were more severe than at 13 weeks. In the stop treatment group receiving MB for 13 weeks, there was regression of the stomach lesion.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Intramural Research (Z01)
Project #
1Z01ES021068-02
Application #
3965205
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
U.S. National Inst of Environ Hlth Scis
Department
Type
DUNS #
City
State
Country
United States
Zip Code