Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Intramural Research (Z01)
Project #
1Z01EY000393-03
Application #
6968570
Study Section
(LI)
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2004
Total Cost
Indirect Cost
Name
U.S. National Eye Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Li, Zhuqing; Liu, Baoying; Maminishkis, Arvydas et al. (2008) Gene expression profiling in autoimmune noninfectious uveitis disease. J Immunol 181:5147-57
Li, Zhuqing; Mahesh, Sankaranarayana P; Shen, De Fen et al. (2006) Eradication of tumor colonization and invasion by a B cell-specific immunotoxin in a murine model for human primary intraocular lymphoma. Cancer Res 66:10586-93
Mahesh, Sankaranarayana P; Li, Zhuqing; Liu, Baoying et al. (2006) Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines. Eur J Immunol 36:2128-38
Liu, Baoying; Li, Zhuqing; Mahesh, Sankaranarayana P et al. (2006) HTLV-1 infection of human retinal pigment epithelial cells and inhibition of viral infection by an antibody to ICAM-1. Invest Ophthalmol Vis Sci 47:1510-5
Li, Zhuqing; Lim, Wee Kiak; Mahesh, Sankaranarayana P et al. (2005) Cutting edge: in vivo blockade of human IL-2 receptor induces expansion of CD56(bright) regulatory NK cells in patients with active uveitis. J Immunol 174:5187-91
Egwuagu, Charles E; Yu, Cheng-Rong; Li, Zhuqing et al. (2005) SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy. J Autoimmun 24:39-46
Mahesh, S P; Li, Zhuqing; Buggage, R et al. (2005) Alpha tropomyosin as a self-antigen in patients with Behcet's disease. Clin Exp Immunol 140:368-75
Kim, Ben J; Li, Zhuqing; Fariss, Robert N et al. (2004) Constitutive and cytokine-induced GITR ligand expression on human retinal pigment epithelium and photoreceptors. Invest Ophthalmol Vis Sci 45:3170-6
Li, Zhuqing; Mahesh, Sankaranarayana P; Kim, Ben J et al. (2003) Expression of glucocorticoid induced TNF receptor family related protein (GITR) on peripheral T cells from normal human donors and patients with non-infectious uveitis. J Autoimmun 21:83-92
McDyer, John F; Li, Zhuqing; John, Susan et al. (2002) IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production. J Immunol 169:2736-46