This project involves methodological research on the analysis of 2x2 contingency table data. The data could originate from a case-control study, or as the result of a vaccine trial. Methods to estimate and test the odds ratio for case-control data or the vaccine efficacy will be investigated. One project constructed unbiased confidence intervals for the odds ratio of case-control exposure data. A method based on the profile likelihood was found to give shorter intervals than existing methods.
Troendle, J F; Frank, J (2001) Unbiased confidence intervals for the odds ratio of two independent binomial samples with application to case-control data. Biometrics 57:484-9 |
Lin, F Y; Azimi, P H; Weisman, L E et al. (2000) Antibiotic susceptibility profiles for group B streptococci isolated from neonates, 1995-1998. Clin Infect Dis 31:76-9 |
Lin, F Y; Vo, A H; Phan, V B et al. (2000) The epidemiology of typhoid fever in the Dong Thap Province, Mekong Delta region of Vietnam. Am J Trop Med Hyg 62:644-8 |