A collaborative linkage study of melanoma families that are not linked to known melanoma loci was inititated in the last fiscal year. Power studies have been performed to pick the most informative families for the search for an additional melanoma locus and genotyping for a genome wide scan has recently been completed on these samples. Analyses of the genome scan have been performed and results will be presented at the upcoming meeting of the Melanoma Consortium. Additonal families are being sought to increase power and additional markers are being genotyped in regions showing suggestive evidence of linkage in the genome scan.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Intramural Research (Z01)
Project #
1Z01HG000112-02
Application #
6109038
Study Section
Special Emphasis Panel (IDRB)
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
National Human Genome Research Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Gillanders, Elizabeth; Juo, Suh-Hang Hank; Holland, Elizabeth A et al. (2003) Localization of a novel melanoma susceptibility locus to 1p22. Am J Hum Genet 73:301-13