Forty adult patients undergoing elective surgical procedures requiring cardiopulmonary bypass will be studied in the perioperative period including the 24 hours immediately following operation. The hypotheses to be tested are: 1) measures of extravascular lung water and colloid osmotic pressure can be used to predict the postoperative clinical respiratory status of patients; and 2) the use of a colloid rather than a crystalloid solution for perioperative fluid resuscitation affects postoperative respiratory function and the need for respiratory support, hemodynamic variables, and cost. Possible adverse effects associated with either fluid resuscitation regimen will be determined.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL002778-02
Application #
3942874
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
U.S. National Heart Lung and Blood Inst
Department
Type
DUNS #
City
State
Country
United States
Zip Code