ULTRA-FAST MRI FOR CARDIOVASCULAR APPLICATIONS We have developed methods for increasing the scanning speed of MRI to allow true real-time visualization of the heart, and to guide interventional therapies. Our efforts have been concentrated in improving both the data acquisition methods (MR pulse sequences and acquisition hardware) and the image reconstruction to provide clear images at greater than 30 frames per second. With these frame rates, cardiac function can be studied without the need for gating, or patient breath-holds. This significantly simplifies the clinical cardiac MR exam, and reduces the overall time required to obtain the data. We have recently imaged the injection of contrast agents directly into the myocardium under real-time MRI guidance. This will soon enable us to deliver therapies such as direct myocardial injection of VEGF , or the application of transmyocardial revascularization, with real-time visualization of the effect on the tissue.
| Nezafat, Reza; Thompson, Richard B; Derbyshire, J Andrew et al. (2006) Partial field-of-view spiral phase-contrast imaging using complex difference processing. Magn Reson Med 56:676-80 |
| Kellman, Peter; McVeigh, Elliot R (2006) Phased array ghost elimination. NMR Biomed 19:352-61 |
| Raval, Amish N; Karmarkar, Parag V; Guttman, Michael A et al. (2006) Real-time magnetic resonance imaging-guided endovascular recanalization of chronic total arterial occlusion in a swine model. Circulation 113:1101-7 |
| Raval, Amish N; Karmarkar, Parag V; Guttman, Michael A et al. (2006) Real-time MRI guided atrial septal puncture and balloon septostomy in swine. Catheter Cardiovasc Interv 67:637-43 |
| McVeigh, Elliot R; Guttman, Michael A; Kellman, Peter et al. (2005) Real-time, Interactive MRI for cardiovascular interventions. Acad Radiol 12:1121-7 |
| Shechter, Guy; Resar, Jon R; McVeigh, Elliot R (2005) Rest period duration of the coronary arteries: implications for magnetic resonance coronary angiography. Med Phys 32:255-62 |
| Herzka, Daniel A; Derbyshire, J Andrew; Kellman, Peter et al. (2005) Single heartbeat cardiac tagging for the evaluation of transient phenomena. Magn Reson Med 54:1455-64 |
| Nezafat, Reza; Kellman, Peter; Derbyshire, J Andrew et al. (2005) Real-time blood flow imaging using autocalibrated spiral sensitivity encoding. Magn Reson Med 54:1557-61 |
| Ennis, Daniel B; Kindlman, Gordon; Rodriguez, Ignacio et al. (2005) Visualization of tensor fields using superquadric glyphs. Magn Reson Med 53:169-76 |
| Larson, Andrew C; Kellman, Peter; Arai, Andrew et al. (2005) Preliminary investigation of respiratory self-gating for free-breathing segmented cine MRI. Magn Reson Med 53:159-68 |
Showing the most recent 10 out of 62 publications
