Human breast cancer cells, MCF-7, were grown in vitro for 2 days in the presence or absence of various doses of interleukin-2 or interleukin-1. Both of these lymphokines have direct effects on the growth of MCF-7 cells. Interleukin-1 has a strictly inhibitory effect on growth, while interleukin-2 has a biphasic effect. At high doses IL-2 inhibits MCF-7 cell growth while at low doses IL-2 actually enhances tumor cell growth.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Intramural Research (Z01)
Project #
1Z01MH002327-01
Application #
3968622
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
U.S. National Institute of Mental Health
Department
Type
DUNS #
City
State
Country
United States
Zip Code