This study examines the sleep architecture (polysomnography) of patients with panic disorder, social phobia, and depression, in comparison with that of normal controls. Continued analysis of such factors as movement time, REM latency, wakefulness after sleep onset, and sleep efficiency among the group is an ongoing focus of research. The study of sleep panic attacks is a major focus of research for the section. Evidence from the sleep laboratory continues to indicate that sleep panic attacks emerge from non- REM sleep-- typically either stage 2 or 3. On the nights when patients have had panic attacks, a prolonged REM latency has been noted, in contrast to the shortened REM latency of depression. End-tidal carbon dioxide is being measured and measures of sleep apnea and nocturnal myoclonus are being employed. New methods of data analysis of sleep records are being developed such as recording number of K-complexes, spindles, and performing spectral analysis of data for between group comparisons. The Section is developing a methodology for quantifying vagal tone during sleep.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Intramural Research (Z01)
Project #
1Z01MH002519-02
Application #
3859986
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
U.S. National Institute of Mental Health
Department
Type
DUNS #
City
State
Country
United States
Zip Code