A number of collaborative efforts involve the investigation of the characteristics of unusual or less debilitating (e.g., headache) neurologic disease phenomena. Unusual associations or space/time clusters of neurologic disorders may provide leads to etiology or therapy. These may be tested through more formal approaches. Surveys of prevalence and natural history and a case-control study of progressive supranuclear palsy (PSP) have been completed in two counties in New Jersey. The point prevalence was 1.39/1 00,000. The median intervals to onset of requiring assistance was 3.1 years and to death, 9.7 years. The case-control study did not implicate a history of stroke, hypertension or smoking as risk factors for PSP. A prevalence survey of migraine in the People's Republic of China yielded a point prevalence ratio of 690/100,000, and indicated that the prevalence ratio for females was higher than that for males.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Intramural Research (Z01)
Project #
1Z01NS002301-15
Application #
3860792
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
15
Fiscal Year
1991
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code