The immunohistochemical observations on compounds related to GABA revealed a widespread reactivity of GABAergic system shortly after the ischemic insult. After 1 week, in relation to severe injury of the nucleus reticularis thalami (NRT), there was beginning of sprouting of new GABAergic terminals observed in the ventral thalamic nuclei (VTN) and it reached its peak at 30 days after ischemia. The sprouting represents a regenerative phenomenon which can be studied further by testing of various drugs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Intramural Research (Z01)
Project #
1Z01NS002832-02
Application #
3846308
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code