Several aspects of susceptibility to audiogenic seizures which develop in rats subjected to cardiac arrest cerebral ischemia have been investigated, revealing some interrelationships between epileptic activity and disinhibition due to dysfunction of certain GABAergic inhibitory systems. Further elucidation of these interrelationships is planned by pharmacological manipulations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Intramural Research (Z01)
Project #
1Z01NS002860-01
Application #
3846336
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code