The correction of chronic mitral insufficiency by conventional mitral valve replacement carries a higher postoperative morbidity and mortality than operations for most other valvular lesions. Clinical studies have shown that valvuloplasty performed to correct mitral insufficiency is associated with a lower morbidity and mortality than with valve replacement. It is suggested that the maintenance of the mitral apparatus (chordae tendinae) prevents enlargement of end-diastolic and end-systolic dimensions. By utilizing each ventricle as its own control, the effect of chordal severance after valve replacement on regional and global geometry was examined. Two groups of animals (chronic and acute) were compared.

Agency
National Institute of Health (NIH)
Institute
Division of Research Services (DRS)
Type
Intramural Research (Z01)
Project #
1Z01RS010247-03
Application #
3959967
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Research Services
Department
Type
DUNS #
City
State
Country
United States
Zip Code