Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC006581-14
Application #
6163282
Study Section
Special Emphasis Panel (M)
Project Start
Project End
Budget Start
Budget End
Support Year
14
Fiscal Year
1997
Total Cost
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Dib, Amel; Glebov, Oleg K; Shou, Yaping et al. (2009) A der(8)t(8;11) chromosome in the Karpas-620 myeloma cell line expresses only cyclin D1: yet both cyclin D1 and MYC are repositioned in close proximity to the 3'IGH enhancer. DNA Repair (Amst) 8:330-5
Dib, Amel; Gabrea, Ana; Glebov, Oleg K et al. (2008) Characterization of MYC translocations in multiple myeloma cell lines. J Natl Cancer Inst Monogr :25-31
Chng, W J; Kuehl, W M; Bergsagel, P L et al. (2008) Translocation t(4;14) retains prognostic significance even in the setting of high-risk molecular signature. Leukemia 22:459-61
Bergsagel, P Leif; Kuehl, W Michael (2008) WSU-WM and BCWM.1 should not be assumed to represent Waldenstrom macroglobulinemia cell lines. Blood 112:917
Kuehl, W Michael (2008) Modeling multiple myeloma by AID-dependent conditional activation of MYC. Cancer Cell 13:85-7
Gabrea, Ana; Martelli, Maria Luisa; Qi, Ying et al. (2008) Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors. Genes Chromosomes Cancer 47:573-90
Dib, Amel; Barlogie, Bart; Shaughnessy Jr, John D et al. (2007) Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma. Blood 109:1337-8
Keats, Jonathan J; Fonseca, Rafael; Chesi, Marta et al. (2007) Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell 12:131-44
Lenz, Georg; Nagel, Inga; Siebert, Reiner et al. (2007) Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma. J Exp Med 204:633-43
Annunziata, Christina M; Davis, R Eric; Demchenko, Yulia et al. (2007) Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12:115-30

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