Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC006670-05
Application #
6163291
Study Section
Surgery (SURG)
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1997
Total Cost
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Cortes, Lizette M; Mattapallil, Mary J; Silver, Phyllis B et al. (2008) Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice. Invest Ophthalmol Vis Sci 49:1946-56
Manjili, Masoud H; Kmieciak, Maciej; Keeler, Johanna (2006) Comment on ""Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma"". J Immunol 176:4511; author reply 4511-2
Zhao, Yangbing; Zheng, Zhili; Cohen, Cyrille J et al. (2006) High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation. Mol Ther 13:151-9
Dudley, Mark E; Wunderlich, John R; Yang, James C et al. (2005) Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 23:2346-57
Wrzesinski, Claudia; Restifo, Nicholas P (2005) Less is more: lymphodepletion followed by hematopoietic stem cell transplant augments adoptive T-cell-based anti-tumor immunotherapy. Curr Opin Immunol 17:195-201
Gattinoni, Luca; Klebanoff, Christopher A; Palmer, Douglas C et al. (2005) Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells. J Clin Invest 115:1616-26
Antony, Paul Andrew; Restifo, Nicholas P (2005) CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2. J Immunother 28:120-8
Chang, Chien-Chung; Campoli, Michael; Restifo, Nicholas P et al. (2005) Immune selection of hot-spot beta 2-microglobulin gene mutations, HLA-A2 allospecificity loss, and antigen-processing machinery component down-regulation in melanoma cells derived from recurrent metastases following immunotherapy. J Immunol 174:1462-71
Zeng, Rong; Spolski, Rosanne; Finkelstein, Steven E et al. (2005) Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. J Exp Med 201:139-48
Restifo, Nicholas P; Rosenberg, Steven A (2005) Use of standard criteria for assessment of cancer vaccines. Lancet Oncol 6:3-4

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