|
Bachman, Ashleigh B; Keramisanou, Dimitra; Xu, Wanping et al. (2018) Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation. Nat Commun 9:265
|
|
Yim, Kendrick H; Prince, Thomas L; Qu, Shiwei et al. (2016) Gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90?. Proc Natl Acad Sci U S A 113:E4801-9
|
|
Calderwood, Stuart K; Neckers, Len (2016) Hsp90 in Cancer: Transcriptional Roles in the Nucleus. Adv Cancer Res 129:89-106
|
|
Prince, Thomas L; Kijima, Toshiki; Tatokoro, Manabu et al. (2015) Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants. PLoS One 10:e0141786
|
|
Sourbier, Carole; Scroggins, Bradley T; Ratnayake, Ranjala et al. (2013) Englerin A stimulates PKC? to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell 23:228-37
|
|
Alarcon, S V; Mollapour, M; Lee, M-J et al. (2012) Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy. Curr Mol Med 12:1125-41
|
|
Xu, Wanping; Neckers, Len (2012) The double edge of the HSP90-CDC37 chaperone machinery: opposing determinants of kinase stability and activity. Future Oncol 8:939-42
|
|
Mollapour, Mehdi; Neckers, Len (2012) Post-translational modifications of Hsp90 and their contributions to chaperone regulation. Biochim Biophys Acta 1823:648-55
|
|
Mollapour, Mehdi; Tsutsumi, Shinji; Truman, Andrew W et al. (2011) Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Mol Cell 41:672-81
|
|
Neckers, Len; Mollapour, Mehdi; Tsutsumi, Shinji (2009) The complex dance of the molecular chaperone Hsp90. Trends Biochem Sci 34:223-6
|
Showing the most recent 10 out of 62 publications
