This project is designed to evaluate the molecular markers in patients that are undergoing radiotherapy in serum and urine. This work is prospective and hypothesis generating. In the previous year we have initiated an international trial of patients with GBMs to determine if urinary VEGF or MMP-2 can help predict outcome. We have collected 34 first samples and expect to collect the 140 samples within the next year. This past year we have worked on standardizing the collection procedures, analysis procedures and the many biomolecules that could incorrectly alter the VEGF levels and have recently sent those manuscripts out for review.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC010372-07
Application #
7594825
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
2007
Total Cost
$915,528
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
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