Abstract

Over the course of the last year the Inflammation and Innate Immunity Unit in the Laboratory of Clinical Infectious Diseases has moved into its temporary BL2 laboratory space on August 10th 2015 inBldg and is in the process of getting set-up to initiate laboratory work and animal studies. Two Post-Doctoral and one post-abc fellow have joined the laboratory. The Inflammation and Innate Immunity Unit has been focusing on purchasing equipment and research supplies as well as initiating the animal study proposals and pathogen registration documents. In addition the move into the designated BL2 space in Bldg 33 is ongoing and a separate BL3 laboratory is in the process of being equipped and set-up.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIAAI001207-02
Application #
9354938
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
Niaid Extramural Activities
Department
Type
DUNS #
City
State
Country
Zip Code

  Publications

Moreira-Teixeira, Lúcia; Mayer-Barber, Katrin; Sher, Alan et al. (2018) Type I interferons in tuberculosis: Foe and occasionally friend. J Exp Med 215:1273-1285
Amaral, Eduardo P; Riteau, Nicolas; Moayeri, Mahtab et al. (2018) Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages. Front Immunol 9:1427
Charmoy, Melanie; Hurrell, Benjamin P; Romano, Audrey et al. (2016) The Nlrp3 inflammasome, IL-1?, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice. Eur J Immunol 46:897-911
Mayer-Barber, Katrin D; Yan, Bo (2016) Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses. Cell Mol Immunol :
Arbore, Giuseppina; West, Erin E; Spolski, Rosanne et al. (2016) T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4? T cells. Science 352:aad1210
McNab, Finlay; Mayer-Barber, Katrin; Sher, Alan et al. (2015) Type I interferons in infectious disease. Nat Rev Immunol 15:87-103
Sionov, Edward; Mayer-Barber, Katrin D; Chang, Yun C et al. (2015) Type I IFN Induction via Poly-ICLC Protects Mice against Cryptococcosis. PLoS Pathog 11:e1005040
Mayer-Barber, Katrin D; Sher, Alan (2015) Cytokine and lipid mediator networks in tuberculosis. Immunol Rev 264:264-75
Mayer-Barber, Katrin D; Barber, Daniel L (2015) Innate and Adaptive Cellular Immune Responses to Mycobacterium tuberculosis Infection. Cold Spring Harb Perspect Med :
Andrade, Bruno B; Pavan Kumar, Nathella; Amaral, Eduardo P et al. (2015) Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis. J Immunol 195:2763-73