We have submitted and have had accepted our proposal for synthesis of a novel imaging probe through the Imaging Probe Development Center (IPDC), which is part of the NHLBI. We have spent time calibrating and optimizing procedures and imaging equipment as well as developing relevant in vivo/animal systems along with in vitro systems for correlative studies. This is a highly collaborative project being pursued with Drs. Murali K. Cherukuri and James B. Mitchell of the Radiation Biology Branch, NCI.
| Kesarwala, Aparna H; Lu, Diana J; Xanthopoulos, Eric et al. (2018) The Role of Advanced Imaging in Assessing Response to Definitive Chemoradiation Before Prophylactic Cranial Irradiation in Limited-Stage Small-Cell Lung Cancer. Clin Lung Cancer 19:e205-e209 |
| Kim, Chul; Hoang, Chuong D; Kesarwala, Aparna H et al. (2017) Role of Local Ablative Therapy in Patients with Oligometastatic and Oligoprogressive Non-Small Cell Lung Cancer. J Thorac Oncol 12:179-193 |
| Takakusagi, Yoichi; Matsumoto, Shingo; Saito, Keita et al. (2014) Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302. PLoS One 9:e107995 |
