The primary objective of this study remains the same: to link the capabilities of people with physical impairments to his or her ability to perform activities of daily living. Many of the methodologies remain the same as well, the core of which is 3D movement analysis. However, the assessment of impairments has been expanded to include assessments of muscle strength, spasticity and muscle size. Balance assessment has also been added. The tasks to be examined have also expanded to include the use of exercise devices and clinical interventions such as electrical simulation as a functional orthoses to improve gait function. We have also reduced the age to birth to allow us to study infant muscles and motor abilities. Data are collected on both healthy volunteers and the target patient groups for some of the interventions. We have collected gait data on different patient groups as well as healthy volunteers, specifically those with cerebral palsy, brachial plexus palsy and adults with dystonia. One paper on muscle strength in individuals with brachial plexus palsy compared to age matched controls was published this year and we are working on another on arm kinematic differences during functional movements across groups.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIACL060017-25
Application #
9154110
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
25
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
Zip Code
Oh, Keonyoung; Stanley, Christopher J; Damiano, Diane L et al. (2018) Biomechanical evaluation of virtual reality-based turning on a self-paced linear treadmill. Gait Posture 65:157-162
Mayfield, Christian H; Kukke, Sahana N; Brochard, Sylvain et al. (2017) Inter-joint coordination analysis of reach-to-grasp kinematics in children and adolescents with obstetrical brachial plexus palsy. Clin Biomech (Bristol, Avon) 46:15-22
Bulea, Thomas C; Stanley, Christopher J; Damiano, Diane L (2017) Part 2: Adaptation of Gait Kinematics in Unilateral Cerebral Palsy Demonstrates Preserved Independent Neural Control of Each Limb. Front Hum Neurosci 11:50
Damiano, Diane L; Stanley, Christopher J; Bulea, Thomas C et al. (2017) Motor Learning Abilities Are Similar in Hemiplegic Cerebral Palsy Compared to Controls as Assessed by Adaptation to Unilateral Leg-Weighting during Gait: Part I. Front Hum Neurosci 11:49
Brochard, Sylvain; Alter, Katharine; Damiano, Diane (2014) Shoulder strength profiles in children with and without brachial PLEXUS PALSY. Muscle Nerve 50:60-6
Terry, Kevin; Stanley, Christopher; Damiano, Diane (2014) A new perspective on the walking margin of stability. J Appl Biomech 30:737-41
Damiano, Diane L; Prosser, Laura A; Curatalo, Lindsey A et al. (2013) Muscle plasticity and ankle control after repetitive use of a functional electrical stimulation device for foot drop in cerebral palsy. Neurorehabil Neural Repair 27:200-7
Damiano, Diane L; Wingert, Jason R; Stanley, Christopher J et al. (2013) Contribution of hip joint proprioception to static and dynamic balance in cerebral palsy: a case control study. J Neuroeng Rehabil 10:57
Prosser, Laura A; Curatalo, Lindsey A; Alter, Katharine E et al. (2012) Acceptability and potential effectiveness of a foot drop stimulator in children and adolescents with cerebral palsy. Dev Med Child Neurol 54:1044-9
Moreau, Noelle G; Falvo, Michael J; Damiano, Diane L (2012) Rapid force generation is impaired in cerebral palsy and is related to decreased muscle size and functional mobility. Gait Posture 35:154-8

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