The ability to record digital video has become much easier and cheaper in recent years, and it is now possible to record round-the-clock video of mice in their home cages, as well as in experimental arenas such as operant boxes. In this project, we are pushing the boundaries of information that can be obtained with such video, and are extracting correlates of weight, size, feeding, and drinking from video analysis, as well as behavioral metrics such as rearing, grooming, walking, resting, etc. This work will support our obesity studies, by giving us access to round-the-clock measurements of these parameters.

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Project End
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Budget End
Support Year
7
Fiscal Year
2019
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Indirect Cost
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Ali, Mohamed A; Kravitz, Alexxai V (2018) Challenges in quantifying food intake in rodents. Brain Res 1693:188-191
Kravitz, Alexxai V; Owen, Scott F; Kreitzer, Anatol C (2013) Optogenetic identification of striatal projection neuron subtypes during in vivo recordings. Brain Res 1511:21-32
Kravitz, Alexxai V; Tye, Lynne D; Kreitzer, Anatol C (2012) Distinct roles for direct and indirect pathway striatal neurons in reinforcement. Nat Neurosci 15:816-8
Kravitz, Alexxai V; Kreitzer, Anatol C (2012) Striatal mechanisms underlying movement, reinforcement, and punishment. Physiology (Bethesda) 27:167-77