Abstract

Diet and other early exposures may affect child development and the risk of several chronic diseases, but additional research is needed. The current research described in this catch-all project comprises one project, described below. We examined the association of a mother's age at menarche with the rate of growth and obesity in her offspring, using data from the Collaborative Perinatal Project. Women with earlier menarche had offspring who, well before puberty, developed more quickly and had higher body mass indexes at a given age. The pattern of growth and body habitus in children is inherited in a manner related to their mother's own sexual maturation. Last years progress: 1 paper was published (see list below).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIAES049021-14
Application #
8149020
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
14
Fiscal Year
2010
Total Cost
$14,847
Indirect Cost

  Institution

Name
National Institute of Environmental Health Sciences
Department
Type
DUNS #
City
State
Country
Zip Code

  Publications

Trabert, Britton; Chodick, Gabriel; Shalev, Varda et al. (2014) Gestational diabetes and the risk of cryptorchidism and hypospadias. Epidemiology 25:152-3
Jensen, Elizabeth T; Longnecker, Matthew P (2014) Pharmacologic sex hormones in pregnancy in relation to offspring obesity. Obesity (Silver Spring) 22:2406-12
Mattsson, K; Källén, K; Longnecker, M P et al. (2013) Maternal smoking during pregnancy and daughters' risk of gestational diabetes and obesity. Diabetologia 56:1689-95
Jukic, Anne Marie Z; Lawlor, Debbie A; Juhl, Mette et al. (2013) Physical activity during pregnancy and language development in the offspring. Paediatr Perinat Epidemiol 27:283-93
Trabert, Britton; Longnecker, Matthew P; Graubard, Barry I et al. (2011) Placental characteristics as a proxy measure of serum hormone and protein levels during pregnancy with a male fetus. Cancer Causes Control 22:689-95
Eggesbø, Merete; Thomsen, Cathrine; Jørgensen, Jens V et al. (2011) Associations between brominated flame retardants in human milk and thyroid-stimulating hormone (TSH) in neonates. Environ Res 111:737-43
Baird, Donna Day; Saldana, Tina M; Nepomnaschy, Pablo A et al. (2010) Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage. J Expo Sci Environ Epidemiol 20:169-75
Basso, O; Pennell, M L; Chen, A et al. (2010) Mother's age at menarche and offspring size. Int J Obes (Lond) 34:1766-71
Ye, Xibiao; Qian, Haojun; Xu, Peicheng et al. (2009) Nephrotoxicity, neurotoxicity, and mercury exposure among children with and without dental amalgam fillings. Int J Hyg Environ Health 212:378-86
Nepomnaschy, Pablo A; Baird, Donna Day; Weinberg, Clarice R et al. (2009) Within-person variability in urinary bisphenol A concentrations: measurements from specimens after long-term frozen storage. Environ Res 109:734-7

Showing the most recent 10 out of 12 publications