The major analyses of the NCS-R dataset during this past year focus on comparisons between adolescent and adult patterns of psychopathology of mania. We have also shown that patterns of mania in adults and youth are remarkably similar. The manuscript is currently under review. In collaboration with B.L. Peterlin, DO, we oversaw the successful publication of a manuscript on episodic migraine and obesity in U.S. adults. The risk of episodic migraine is likely increased in individuals with obesity, and is more pronounced among those younger than 50 years, those who are white, and women (Peterlin et al, 2013). Public Health Impact: These findings have provided important information on links between health problems and migraine that may be used to guide prevention and treatment of migraine. Future Plans: Our efforts on the NCS-R as an independent project have been significantly reduced over the years, since the analyses of the most relevant topics to our research programs have been completed and our main research target population is children and adolescents. However, we plan to continue to work with these data from this rich nationally representative sample to conduct comparative analyses of symptom patterns, correlates and consequences of disorders shown in our parallel adolescent sample.

Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
2014
Total Cost
Indirect Cost
Name
U.S. National Institute of Mental Health
Department
Type
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Rao, Aruna S; Scher, Ann I; Vieira, Rebeca V A et al. (2015) The Impact of Post-Traumatic Stress Disorder on the Burden of Migraine: Results From the National Comorbidity Survey-Replication. Headache 55:1323-41
Peterlin, B Lee; Rosso, Andrea L; Williams, Michelle A et al. (2013) Episodic migraine and obesity and the influence of age, race, and sex. Neurology 81:1314-21
Merikangas, Kathleen R (2013) Contributions of epidemiology to our understanding of migraine. Headache 53:230-46
Merikangas, Kathleen R; McClair, Vetisha L (2012) Epidemiology of substance use disorders. Hum Genet 131:779-89
Lamers, Femke; Burstein, Marcy; He, Jian-ping et al. (2012) Structure of major depressive disorder in adolescents and adults in the US general population. Br J Psychiatry 201:143-50
Fiedorowicz, Jess G; He, Jianping; Merikangas, Kathleen R (2011) The association between mood and anxiety disorders with vascular diseases and risk factors in a nationally representative sample. J Psychosom Res 70:145-54
Lateef, Tarannum; Swanson, Sonja; Cui, Lihong et al. (2011) Headaches and sleep problems among adults in the United States: findings from the National Comorbidity Survey-Replication study. Cephalalgia 31:648-53
Swendsen, Joel; Conway, Kevin P; Degenhardt, Louisa et al. (2010) Mental disorders as risk factors for substance use, abuse and dependence: results from the 10-year follow-up of the National Comorbidity Survey. Addiction 105:1117-28
Nierenberg, A A; Akiskal, H S; Angst, J et al. (2010) Bipolar disorder with frequent mood episodes in the national comorbidity survey replication (NCS-R). Mol Psychiatry 15:1075-87
Angst, Jules; Cui, Lihong; Swendsen, Joel et al. (2010) Major depressive disorder with subthreshold bipolarity in the National Comorbidity Survey Replication. Am J Psychiatry 167:1194-201

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