Under NCT03388606, we have: 1. Screened: 763 potential MDD patients, 200 HVs 2. Enrolled: 104 MDD patients, 70 HVs (including in other protocols) 3. Scanned: 452 MDD and HVs in total, including repeated scans on same individual as part of follow-up. 4. Increased inpatient activity: this protocol has already accounted for nearly 500 inpatient days 5. Continued outpatient activity: this protocol has seen over 200 more outpatient visits than the program recorded in FY17 for the same time period. 6. Published several papers in the last year The most notable include two last-author papers in the American Journal of Psychiatry (Pornpattatanangkul et al 2019, JAMA Psychiatry) and a trial paper (Towbin et al 2019 JAACAP).

Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2019
Total Cost
Indirect Cost
Name
U.S. National Institute of Mental Health
Department
Type
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Villalta, L; Smith, P; Hickin, N et al. (2018) Emotion regulation difficulties in traumatized youth: a meta-analysis and conceptual review. Eur Child Adolesc Psychiatry 27:527-544
Brislin, Sarah J; Patrick, Christopher J; Flor, Herta et al. (2018) Extending the Construct Network of Trait Disinhibition to the Neuroimaging Domain: Validation of a Bridging Scale for Use in the European IMAGEN Project. Assessment :1073191118759748
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Kircanski, Katharina; White, Lauren K; Tseng, Wan-Ling et al. (2018) A Latent Variable Approach to Differentiating Neural Mechanisms of Irritability and Anxiety in Youth. JAMA Psychiatry 75:631-639
Keren, Hanna; Chen, Gang; Benson, Brenda et al. (2018) Is the encoding of Reward Prediction Error reliable during development? Neuroimage 178:266-276
Barker, Edward D; Walton, Esther; Cecil, Charlotte A M et al. (2018) A Methylome-Wide Association Study of Trajectories of Oppositional Defiant Behaviors and Biological Overlap With Attention Deficit Hyperactivity Disorder. Child Dev 89:1839-1855

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