The goal of this effort is to use various bioinformatics approaches to analyze data regarding complex human disease, aging, and the role of disease processes in aging. Over the years we have applied this effort to a number of related projects including The Genetic Association Database, development of disease related Gene Sets for multiplex analysis of high-throughput data, among others. This includes summaries of genetic associations for Type 2 Diabetes, Alzheimer's disease, Obesity, Autoimmune diseases, among many others. We are currently using a bioinformatic approach to analyze population based aging related studies based on methylation and large scale gene expression studying increasing genomic instability with age.
| Becker, Kevin G (2018) Autism and Socioeconomic Status-An Immune Link? Am J Public Health 108:e16 |
| Panda, Amaresh C; Abdelmohsen, Kotb; Martindale, Jennifer L et al. (2016) Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis. Nucleic Acids Res 44:2393-408 |
| Tsuchiya, Motohiro; Kalurupalle, Swathi; Kumar, Parameet et al. (2016) RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF. RNA Biol 13:837-47 |
| Noren Hooten, Nicole; Martin-Montalvo, Alejandro; Dluzen, Douglas F et al. (2016) Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence. Aging Cell 15:572-81 |
| Zhang, Peisu; Abdelmohsen, Kotb; Liu, Yong et al. (2015) Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity. Nat Commun 6:8888 |
| De, Supriyo; Zhang, Yongqing; Wolkow, Catherine A et al. (2013) Genome-wide modeling of complex phenotypes in Caenorhabditis elegans and Drosophila melanogaster. BMC Genomics 14:580 |
| Arighi, Cecilia N; Carterette, Ben; Cohen, K Bretonnel et al. (2013) An overview of the BioCreative 2012 Workshop Track III: interactive text mining task. Database (Oxford) 2013:bas056 |
| Becker, Kevin G (2012) Male gender bias in autism and pediatric autoimmunity. Autism Res 5:77-83 |
| Becker, Kevin G (2011) Autism, immune dysfunction and Vitamin D. Acta Psychiatr Scand 124:74; author reply 74-5 |
| Becker, Kevin G; Holmes, Karen A; Zhang, Yongqing (2011) Aging-kb: a knowledge base for the study of the aging process. Mech Ageing Dev 132:592-4 |
Showing the most recent 10 out of 15 publications
