During 2010-2011, the Protein Chemistry Core (PCC) provided services to investigators in the NCI-CCR as well as other NIH institutes. In addition, the PCC collaborated with laboratories in the extramural community. 102 samples were processed for N-terminal peptide sequencing. 65 samples were processed for HPLC peptide analysis. 8 samples were processed for peptide digestion. 52 samples were processed for phosphoamino acid analysis. 45 samples were processed for 2D gel electrophoresis. 42 2D-gels were stained or transferred to immobilon for further analysis.
| Sarkar, Tapasree Roy; Sharan, Shikha; Wang, Jun et al. (2012) Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBP? expression and contributes to transformation of breast tumor cells. Mol Cell Biol 32:320-32 |
| Ritt, Daniel A; Monson, Daniel M; Specht, Suzanne I et al. (2010) Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling. Mol Cell Biol 30:806-19 |
| Dougherty, Michele K; Ritt, Daniel A; Zhou, Ming et al. (2009) KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals. Mol Cell 34:652-62 |
| McKay, Melissa M; Ritt, Daniel A; Morrison, Deborah K (2009) Signaling dynamics of the KSR1 scaffold complex. Proc Natl Acad Sci U S A 106:11022-7 |
