Abstract

During the past year, the MGC provided sequencing for 35 projects across the full spectrum of sequencing types (RNA-Seq, microRNA-Seq, whole exome sequencing, whole genome sequencing, ChIP-Seq, methyl-Seq, MNase-Seq, microbiome sequencing, ribosomal profiling, and others); the projects involved 19 NICHD Principal Investigators. In addition to sequencing and providing our standard primary bioinformatic analysis of the resulting data, the MGC delivered enhanced bioinformatic support throughout the NICHD.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Scientific Cores Intramural Research (ZIC)
Project #
1ZICHD008958-01
Application #
9353164
Study Section
Program Officer
Hewitt, Tyl
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
U.S. National Inst/Child Hlth/Human Dev
Department
Type
DUNS #
City
State
Country
Zip Code

  Publications

Suzuki, Shigeru; Iben, James R; Coon, Steven L et al. (2018) SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity. Mol Cell Endocrinol 461:178-187
Backlund, Peter S; Urbanski, Henryk F; Doll, Mark A et al. (2017) Daily Rhythm in Plasma N-acetyltryptamine. J Biol Rhythms 32:195-211
Zhang, Kai; Ruan, Zhiqiang; Li, Jia et al. (2017) A Comparative Genomic and Transcriptomic Survey Provides Novel Insights into N-Acetylserotonin Methyltransferase (ASMT) in Fish. Molecules 22:
Hartley, Stephen W; Mullikin, James C; Klein, David C et al. (2016) Alternative Isoform Analysis of Ttc8 Expression in the Rat Pineal Gland Using a Multi-Platform Sequencing Approach Reveals Neural Regulation. PLoS One 11:e0163590
Li, Jia; You, Xinxin; Bian, Chao et al. (2016) Molecular Evolution of Aralkylamine N-Acetyltransferase in Fish: A Genomic Survey. Int J Mol Sci 17:
Wassif, Christopher A; Cross, Joanna L; Iben, James et al. (2016) High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets. Genet Med 18:41-8
Arimbasseri, Aneeshkumar G; Iben, James; Wei, Fan-Yan et al. (2016) Evolving specificity of tRNA 3-methyl-cytidine-32 (m3C32) modification: a subset of tRNAsSer requires N6-isopentenylation of A37. RNA 22:1400-10
Peng, Chao; Yao, Ge; Gao, Bing-Miao et al. (2016) High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing. Gigascience 5:17
Lamichhane, Tek N; Arimbasseri, Aneeshkumar G; Rijal, Keshab et al. (2016) Lack of tRNA-i6A modification causes mitochondrial-like metabolic deficiency in S. pombe by limiting activity of cytosolic tRNATyr, not mito-tRNA. RNA 22:583-96
Gebert, Claudia; Rong, Qi; Jeong, Sangkyun et al. (2016) H19ICR mediated transcriptional silencing does not require target promoter methylation. Biochem Biophys Res Commun 476:121-6

Showing the most recent 10 out of 18 publications