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The entirety of funding information.
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Gene Therapy and the Brain: Neuroimmune InteractionsGene therapy provides exciting new approaches to treat numerous incurable neurodegenerative disorders such as Parkinson's disease, multiple sclerosis, or brain cancer. Unfortunately the immune response to therapeutic vectors remains a...
Superantigen-Induced Vascular Injury and DICSuperantigens are extremely potent stimulators of T lymphocytes that produce a myriad of proinflammatory cytokines known to induce vascular injury, collapse of vascular system (toxic shock syndrome), and disseminated intravascular...
Physiological Mr Studies Using Hyperpolarized 129xeThe noble gas xenon is a safe and effective general anesthetic. Rapidly absorbed via the lung into the blood-stream, it concentrates in lipid- rich tissue with a time-dependence related to...
Glycosylation Mutants of Animal CellsIn order to investigate structure/function relationships of animal cell carbohydrates, as series of glycosylation mutants of Chinese hamster ovary (CHO) cells have been isolated. All of the mutants exhibit altered...
Neuromodulation of Neuronal OscillationsNeuromodulators provide flexibility for neural circuit operation and behavior. Yet, at any given time, neural circuits are subject to modulation by multiple neurotransmitters and neurohormones. Each modulator elicits its own...
High throughput marker for cognitive deficit: cellular autofluorescenceFor the past decade, several lines of evidence have shown a direct role for oxidative stress in the pathology of schizophrenia (SZ). Although peripheral changes associated with oxidative stress may...
Characterization of the role of Fmr1 in oxytocin neuronal subtypesThis revised R01 application focuses on elucidating the cell type specific functions of the Fmr1 gene in the pathogenesis of social impairments that characterize autism spectrum disorder (ASD); a first...
Effects of prenatal maternal depression and antidepressant exposures on offspring neurodevelopmental trajectories: A birth cohort studyThis new R01 aims to study the effects of selective serotonin reuptake inhibitor (SSRI) antidepressant medication use by women in pregnancy on their offspring?s brain and cognitive development in the...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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