Treating alcohol dependence is a great unmet need worldwide and developing medications to treat alcohol dependence remains a high priority of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). To help fulfill this goal, NIAAA has implemented a preclinical medication screening program to foster discovery of lead compounds, targets and mechanisms, and to entice the pharmaceutical industry to develop their best marketable compounds for alcoholism treatment. Previously, ?proof-of-principle? studies were conducted to demonstrate the feasibility for successful testing using the clinically effective compounds naltrexone and acamprosate in rodent models of dispositional heavy drinking. The current contract seeks to test potential medications in heavy drinking paradigms which have demonstrated utility for medication screening.

Agency
National Institute of Health (NIH)
Type
Research and Development Contracts (N01)
Project #
267200700038C-4-0-1
Application #
8756370
Study Section
Project Start
2007-09-28
Project End
2014-03-31
Budget Start
Budget End
Support Year
Fiscal Year
2013
Total Cost
$300,000
Indirect Cost
Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425