Syphilis has become the most commonly reported communicable disease in most major cities of South China, drawing attention to the resurgence of STDs all over the country. This unique region has massive rural-to- urban migration and poverty, yet also holds exceptional domestic resources for STD control. Drawing on a long history of collaborative US-China STD training and research, this training grant will formalize the UNC- South China STD Research Training Center. The Center will focus on classical STDs (syphilis, gonorrhea, chlamydia, HIV, human papillomavirus) as well as hepatitis B and hepatitis C. STD pathogenesis, clinical science, epidemiology, and social science will be included. Incorporating social and policy STD expertise within the Training Center faculty acknowledges the broader policy and development issues that must be part of successful US-China collaboration and positions the initiative within a larger health diplomacy framework. A rich history of UNC-trained physicians leading STD training in China and a growing pool of UNC-trained STD mentors create a strong foundation for UNC Project-China to build this Training Center. UNC and local South China consortia partners (Guangdong STD Control Center, Number Eight People's Hospital, and Sun Yat-sen University) will launch the first 10-day STD research training course in May 2012 with 30 selected junior Chinese investigators, 12 UNC training faculty, and 14 Chinese training faculty. This D43 grant will then support qualified junio Chinese investigators to take part in the following annually repeated sequence: 1) subsequent iterations of an intensive 10-day course short-term training course building research capacity and linking mentees with mentors;2) among six selected qualified trainees who complete short-term training, medium-term training (3-6 months) focused on preparing research protocols and obtaining ethical approval;3) among six selected qualified trainees who have completed medium-term training, long-term (1-2 years) training focused on undertaking mentored STD research and enhancing career development. Separate pathways for predoctoral trainees, postdoctoral trainees, and MD trainees acknowledge their distinct training needs and different career trajectories. Our Center unites STD medicine, public health, and implementation in order to improve multidisciplinary research capacity and increase the likelihood of junior Chinese investigators directly applying for Chinese and US grants. A substantial resource commitment from Guangzhou consortia partners increases the likelihood of success.

Public Health Relevance

PUBLIC HEALTH RELEVANCE: China has a substantial burden of STDs that demand further research and training. This research training grant will nurture the development of the next generation of STD research leaders in South China.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW009532-02S1
Application #
8921510
Study Section
Special Emphasis Panel (ZRG1-IDM-U (57))
Program Officer
Sina, Barbara J
Project Start
2013-07-12
Project End
2018-01-31
Budget Start
2014-02-01
Budget End
2015-01-31
Support Year
2
Fiscal Year
2014
Total Cost
$50,000
Indirect Cost
$3,111
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Das, Aritra; Li, Jianjun; Zhong, Fei et al. (2015) Factors associated with HIV and syphilis co-infection among men who have sex with men in seven Chinese cities. Int J STD AIDS 26:145-55
Tang, Weiming; Babu, Giridhara R; Li, Jianjun et al. (2015) The difference between HIV and syphilis prevalence and incidence cases: results from a cohort study in Nanjing, China, 2008-2010. Int J STD AIDS 26:648-55
Han, Larry; Bien, Cedric H; Wei, Chongyi et al. (2014) HIV self-testing among online MSM in China: implications for expanding HIV testing among key populations. J Acquir Immune Defic Syndr 67:216-21
Liu, Xiao-Yan; Hao, Chao; Jiang, Hui et al. (2014) Syphilis and its correlates among heterosexual males attending sexually transmitted infection clinics - observation from a multicity cohort in Jiangsu Province, China. PLoS One 9:e95289
Feng, Yi; Wei, Huamian; Hsi, Jenny et al. (2014) Identification of a novel HIV Type 1 circulating recombinant form (CRF65_cpx) composed of CRF01_AE and subtypes B and C in Western Yunnan, China. AIDS Res Hum Retroviruses 30:598-602
Yang, Hai-Tao; Tang, Weiming; Xiao, Zhan-Pei et al. (2014) Worsening epidemic of HIV and syphilis among men who have sex with men in Jiangsu Province, China. Clin Infect Dis 58:1753-9
Fu, Geng-Feng; Pan, Ji-Cheng; Lin, Nan et al. (2014) siRNA against KIR3DL1 as a potential gene therapeutic agent in controlling HIV-1 infection. Viral Immunol 27:207-13
Hall, Brian J; Chen, Wen; Latkin, Carl et al. (2014) Africans in south China face social and health barriers. Lancet 383:1291-2
Wei, Chongyi; Muessig, Kathryn E; Bien, Cedric et al. (2014) Strategies for promoting HIV testing uptake: willingness to receive couple-based and collective HIV testing among a cross-sectional online sample of men who have sex with men in China. Sex Transm Infect 90:469-74
Wang, Lu; Tang, Weiming; Wang, Lan et al. (2014) The HIV, syphilis, and HCV epidemics among female sex workers in china: results from a serial cross-sectional study between 2008 and 2012. Clin Infect Dis 59:e1-9

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