The scientific goal of this project is to use magnetoencephalography (MEG) to gain a better understanding of the cortical networks involved in phonetic processing. Cortical sources involved in phonetic processing using whole-head MEG shall be investigated using novel tools to reconstruct their locations and time courses. Key technical developments to facilitate this work include methods to co-register and normalize MEG, ECoG, and structural MRI data. Cortical network connectivity during phonetic processing will also be examined using neural source reconstructions. To the extent possible, all analyses will be cross-validated with ECoG recordings in brain tumor patients. This project provides an interdisciplinary approach to studying important issues of neuronal activation and connectivity, using a multitude of techniques such as MEG, ECoG, and MRI. It also supports translational research with the potential to improve preoperative clinical language mapping procedures.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31DC006762-03
Application #
7036561
Study Section
Communication Disorders Review Committee (CDRC)
Program Officer
Sklare, Dan
Project Start
2004-03-19
Project End
2007-03-18
Budget Start
2006-03-19
Budget End
2007-03-18
Support Year
3
Fiscal Year
2006
Total Cost
$28,975
Indirect Cost
Name
University of California San Francisco
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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