This study will examine the biomechanics of the hip in normal and dysplastic patients, specifically focusing on patients with """"""""traditional"""""""" dysplasia versus those with a dysplastic retroverted acetabulum. Patient-specific finite element models will be used to predict contact areas, maximum cartilage stresses and maximum bone stresses and their locations for three patient groups (normal, traditional dysplastic, retroverted dysplastic). The rationale for this study stems from the fact that acetabular dysplasia may be the leading cause of premature osteoarthritis of the hip; however, the exact relationships between the altered geometries associated with different types of dysplasia and the resulting stresses in the joint are poorly understood. The literature that has examined the relationships between acetabular dysplasia and development of hip osteoarthritis is contradictory. The overall objective of this study is to elucidate the biomechanical differences in hip joint loading and stresses in patients with normal hips, """"""""traditional"""""""" dysplastic hips and hips with dysplasia characterized by retroversion of the acetabulum during simulated single-leg stance and stair climbing. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
1F31EB005551-01A2
Application #
7111903
Study Section
Special Emphasis Panel (ZRG1-F10-H (20))
Program Officer
Baird, Richard A
Project Start
2006-03-01
Project End
2009-02-28
Budget Start
2006-03-01
Budget End
2007-02-28
Support Year
1
Fiscal Year
2006
Total Cost
$35,637
Indirect Cost
Name
University of Utah
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Fiorentino, Niccolo M; Kutschke, Michael J; Atkins, Penny R et al. (2016) Accuracy of Functional and Predictive Methods to Calculate the Hip Joint Center in Young Non-pathologic Asymptomatic Adults with Dual Fluoroscopy as a Reference Standard. Ann Biomed Eng 44:2168-80
Kapron, Ashley L; Aoki, Stephen K; Peters, Christopher L et al. (2014) Accuracy and feasibility of dual fluoroscopy and model-based tracking to quantify in vivo hip kinematics during clinical exams. J Appl Biomech 30:461-70
Anderson, Andrew E; Ellis, Benjamin J; Maas, Steve A et al. (2008) Validation of finite element predictions of cartilage contact pressure in the human hip joint. J Biomech Eng 130:051008