The long-term objective of the current research proposal is to provide a foundation of knowledge on the neural correlates of cognitive biases in social phobia in order to better inform clinically relevant issues such as nosology, diagnostics, treatment, and prevention. As a first major step towards achieving this long-term goal, the aims of the current study involve applying knowledge from experimental psychophysiology and cognitive science to the investigation of cognitive biases in adult psychopathology. Specifically, the current study aims are to utilize event-related brain potentials (ERPs) to examine cognitive biases implicated in the development and maintenance of social phobia and to identify those biases that are specific to social phobia (SP) by comparing them to those present in patients with major depressive disorder (MDD), as data suggest social anxiety and depression may manifest in similar ways, but the underlying cognitive mechanisms may be different. This will be accomplished by recording attentional allocation and response monitoring ERPs while patients with SP, patients with MDD and normal control participants perform two speeded reaction time tasks. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
1F31MH077388-01A1
Application #
7217000
Study Section
Special Emphasis Panel (ZRG1-F12B-G (20))
Program Officer
Rubio, Mercedes
Project Start
2006-09-25
Project End
2008-09-24
Budget Start
2006-09-25
Budget End
2007-09-24
Support Year
1
Fiscal Year
2006
Total Cost
$29,601
Indirect Cost
Name
University of Delaware
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Moser, Jason S; Huppert, Jonathan D; Foa, Edna B et al. (2012) Interpretation of ambiguous social scenarios in social phobia and depression: evidence from event-related brain potentials. Biol Psychol 89:387-97
Moser, Jason S; Most, Steven B; Simons, Robert F (2010) Increasing negative emotions by reappraisal enhances subsequent cognitive control: a combined behavioral and electrophysiological study. Cogn Affect Behav Neurosci 10:195-207
Simons, Robert F (2010) The way of our errors: theme and variations. Psychophysiology 47:1-14
Moser, Jason S; Krompinger, Jason W; Dietz, Jenna et al. (2009) Electrophysiological correlates of decreasing and increasing emotional responses to unpleasant pictures. Psychophysiology 46:17-27
Moser, Jason S; Simons, Robert F (2009) The neural consequences of flip-flopping: the feedback-related negativity and salience of reward prediction. Psychophysiology 46:313-20
Moser, Jason S; Hajcak, Greg; Huppert, Jonathan D et al. (2008) Interpretation bias in social anxiety as detected by event-related brain potentials. Emotion 8:693-700
Moser, Jason S; Huppert, Jonathan D; Duval, Elizabeth et al. (2008) Face processing biases in social anxiety: an electrophysiological study. Biol Psychol 78:93-103