The proposed research is designed to investigate the neural substrates of source monitoring, which involve judgments about the source of retrieved memories. Source judgments are based on memory characteristics such as perceptual information, temporal context and cognitive operations. It is hypothesized that the dorsolateral prefrontal cortex is critical to this source judgment process and that there will be hemispheric differences in activation of this region based on the memory characteristics on which a particular judgment rely. Converging evidence from two methodologies will be used to elucidate hemispheric and regional contributions to the source monitoring process. Split-brain testing and functional magnetic resonance imaging will be used in a series of experiments that manipulate specific characteristics of memories to test the experimental hypotheses.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32NS010642-01A1
Application #
2793062
Study Section
Special Emphasis Panel (ZRG1-IFCN-8 (01))
Program Officer
Edwards, Emmeline
Project Start
1999-01-01
Project End
Budget Start
1999-01-01
Budget End
1999-12-31
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Funnell, Margaret G; Colvin, Mary K; Gazzaniga, Michael S (2007) The calculating hemispheres: studies of a split-brain patient. Neuropsychologia 45:2378-86
Colvin, Mary K; Funnell, Margaret G; Gazzaniga, Michael S (2005) Numerical processing in the two hemispheres: studies of a split-brain patient. Brain Cogn 57:43-52
Frey, Scott H; Funnell, Margaret G; Gerry, Valerie E et al. (2005) A dissociation between the representation of tool-use skills and hand dominance: insights from left- and right-handed callosotomy patients. J Cogn Neurosci 17:262-72
Funnell, Margaret G; Corballis, Paul M; Gazzaniga, Michael S (2003) Temporal discrimination in the split brain. Brain Cogn 53:218-22
Corballis, Paul M; Funnell, Margaret G; Gazzaniga, Michael S (2002) An investigation of the line motion effect in a callosotomy patient. Brain Cogn 48:327-32
Corballis, Paul M; Funnell, Margaret G; Gazzaniga, Michael S (2002) Hemispheric asymmetries for simple visual judgments in the split brain. Neuropsychologia 40:401-10
Funnell, M G; Corballis, P M; Gazzaniga, M S (2001) Hemispheric processing asymmetries: implications for memory. Brain Cogn 46:135-9
Corballis, P M; Inati, S; Funnell, M G et al. (2001) MRI assessment of spared fibers following callosotomy: a second look. Neurology 57:1345-6