After twenty eight years of support through the RCM! Program, the institution has greatly benefited from the improvement in;the number and quality of the peer-reviewed manuscripts elicited by the faculty, the number of scientific presentations at competitive forums at the national as well as international levels, and in the number of submitted and funded research and research training initiatives. In furthering with these efforts, the institution is submitting the present renewal application. Its main goal is to promote high quality translational research with a strong emphasis in health disparities. The present application consists of four Core activities;Administration, AIDS Research Infrastructure, Molecular Biology and Genomics, and the Behavioral Research and Integrated Neurosciences. The Administrative Core is intended to spearhead a series of initiatives designed to strengthen the institution as a robust and vibrant translational research center, and to further developing our research faculty into independent and competent biomedical researchers. These initiatives include the organization and inception of;a Research Pilot Project Program to sponsor innovative clinical and translational activities;professional development activities (seminar series, workshops, short courses, mentoring efforts, etc.;a faculty recruitment program, a mentoring program, and efforts to enhance research collaborations and partnerships between PSM and other RCMI as well as Non-RCMI Institutions;The proposed new RCMI Program at PSM will experience the benefits of a well- integrated and committed administrative structure. The proposed leadership for this new RCMI Program will use the multiple PIs option. Thus, Dr. Jose A. Torres-Ruiz, Director of the Ph.D. Program in the Biomedical Sciences, and Chair of the Department of Biochemistry, will serve as the Contact PI, whereas Dr. Richard Noel, Jr. will serve as the second PI. The working relationship of these two professionals is excellent. Both academic leaders are well respected among their peers and the top administrative officials at the School. Furthermore, the RCMI Program at the institution will receive the support of an Executive Program Manager, Ms. Claris A. Vega, MBA, an experienced and accomplished grants administrator. The RCMI Program will benefit from a very supportive institutional commitment.

Public Health Relevance

The proposed RCMI Program at the Ponce School of Medicine constitutes a comprehensive effort designed to advance the agenda contemplated in our Institutional Strategic Plan for Research for the next five years. Along these lines, one of th major goals contained in this strategic plan is to develop the necessary research infrastructure at PSM in order for its investigators to significantly contribute to the elimination of health disparities in disadvantaged populations at the local as well as the national levels.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12MD007579-29
Application #
8667758
Study Section
Special Emphasis Panel (ZMD1-MLS (01))
Program Officer
Zhang, Xinzhi
Project Start
1997-08-25
Project End
2019-03-31
Budget Start
2014-06-01
Budget End
2015-03-31
Support Year
29
Fiscal Year
2014
Total Cost
$2,358,849
Indirect Cost
$720,000
Name
Ponce School of Medicine
Department
Type
DUNS #
105742043
City
Ponce
State
PR
Country
United States
Zip Code
00732
Rivera-Rivera, Yainyrette; Vázquez-Santiago, Fabián J; Albino, Elinette et al. (2016) Impact of Depression and Inflammation on the Progression of HIV Disease. J Clin Cell Immunol 7:
Hou, Wangheng; Torres, Lilith; Cruz-Cosme, Ruth et al. (2016) Two Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human Cytomegalovirus. J Virol 90:7339-49
de Jesus, Edelmarie Rivera; Isidro, Raymond A; Cruz, Myrella L et al. (2016) Adoptive Transfer of Dendritic Cells Expressing Fas Ligand Modulates Intestinal Inflammation in a Model of Inflammatory Bowel Disease. J Clin Cell Immunol 7:
López, Pablo; Rivera-Amill, Vanessa; Rodríguez, Nayra et al. (2016) The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico. Int J Environ Res Public Health 13:ijerph13010055
Ortiz, Carmen; Morales, Luisa; Sastre, Miguel et al. (2016) Cytotoxicity and Genotoxicity Assessment of Sandalwood Essential Oil in Human Breast Cell Lines MCF-7 and MCF-10A. Evid Based Complement Alternat Med 2016:3696232
Ortiz, Maricelly Santiago; Forti, Kevin Muñoz; Suárez Martinez, Edu B et al. (2016) Effects of Antioxidant N-acetylcysteine Against Paraquat-Induced Oxidative Stress in Vital Tissues of Mice. Int J Sci Basic Appl Res 26:26-46
Noel, Richard J; Kaul, Marcus (2016) The 22nd Scientific Conference of the Society on Neuroimmune Pharmacology. J Neuroimmune Pharmacol 11 Suppl 1:S1-2
Torres-Reverón, Annelyn; Palermo, Karylane; Hernández-López, Anixa et al. (2016) Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray. Reprod Sci 23:1158-67
Quiñones, María M; Maldonado, Lizette; Velazquez, Bethzaly et al. (2016) Candesartan ameliorates impaired fear extinction induced by innate immune activation. Brain Behav Immun 52:169-77
Abreu-Delgado, Yamilka; Isidro, Raymond A; Torres, Esther A et al. (2016) Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease. World J Gastroenterol 22:3581-91

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