Behavioral Testing Facility The main goal of the Behavioral Testing Facility (BTF) is to cover a need associated with the development of the basic sciences and clinical community at the Universidad Central del Caribe (UCC). Additionally, BTF has extended its services to all Puerto Rico's entire scientific community. We are proposing five specific aims for the renewal proposal.
Specific Aim 1. To foster the usage of BTF by basic scientists and clinicians in Puerto Rico. Enhancement in the use of the facility will be addressed by the integration of two additional functional units within the BTF core: the Human Behavioral Phenotyping Unit (HBPU) and the Animal Behavioral Phenotyping Unit (ABPU).
Specific Aim 2. To continue providing highly productive working conditions for the use of the existing equipment and the environment necessary for both ongoing and new projects oriented to translational research.
Specific Aim 3. To continue the training of research assistants and other personnel and BTF's users in methods, equipment, experimental protocols and software used in behavioral experiments. This training will include new internet based methodologies to provide even greater access to our facilities.
Specific Aim 4. To intensify the collaborative research at the UCC community, and between UCC and other local and Continental USA Universities, by effectively marketing the facility through the cooperative research network """"""""Research Centers in Minority Institutions Translational Research Network"""""""" ( which is facilitating the translational research in health disparity areas.
Specific Aim 5. To help the scientific community involved in experiments to acquire data and visualize animal behavior and/or psychomotor alteration related to translational research by maintaining updated the analytical methodologies. Our Behavioral Testing Facility has served >30 researchers, and currently 10 investigators are using the facility Four new proposals recently submitted to federal agencies are including usage of BTF in their experiments.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Research Centers in Minority Institutions Award (G12)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Universidad Central Del Caribe
United States
Zip Code
Buchacz, Kate; Lau, Bryan; Jing, Yuezhou et al. (2016) Incidence of AIDS-Defining Opportunistic Infections in a Multicohort Analysis of HIV-infected Persons in the United States and Canada, 2000-2010. J Infect Dis 214:862-72
Fred-Jiménez, Ruth M; Arroyo-Ávila, Mariangelí; Mayor, Ángel M et al. (2016) Clinical Manifestations Associated with Overweight/Obesity in Puerto Ricans with Fibromyalgia Syndrome. J Obes 2016:1379289
Méndez-González, Miguel P; Kucheryavykh, Yuriy V; Zayas-Santiago, Astrid et al. (2016) Novel KCNJ10 Gene Variations Compromise Function of Inwardly Rectifying Potassium Channel 4.1. J Biol Chem 291:7716-26
Santiago-Rodríguez, Eduardo J; Mayor, Angel M; Fernández-Santos, Diana M et al. (2016) Profile of HIV-Infected Hispanics with Pancytopenia. Int J Environ Res Public Health 13:ijerph13010038
Inyushin, M; Kucheryavih, Yu; Kucheryavih, L et al. (2016) Superparamagnetic Properties of Hemozoin. Sci Rep 6:26212
Morales-Cruz, Moraima; Cruz-Montañez, Alejandra; Figueroa, Cindy M et al. (2016) Combining Stimulus-Triggered Release and Active Targeting Strategies Improves Cytotoxicity of Cytochrome c Nanoparticles in Tumor Cells. Mol Pharm 13:2844-54
Rivera Rivera, Amilcar; Castillo-Pichardo, Linette; Gerena, Yamil et al. (2016) Anti-Breast Cancer Potential of Quercetin via the Akt/AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Cascade. PLoS One 11:e0157251
Althoff, Keri N; Rebeiro, Peter F; Hanna, David B et al. (2016) A picture is worth a thousand words: maps of HIV indicators to inform research, programs, and policy from NA-ACCORD and CCASAnet clinical cohorts. J Int AIDS Soc 19:20707
Miranda-Diaz, Christine; Betancourt, Elba; Ruiz-Candelaria, Yelitza et al. (2016) Barriers for Compliance to Breast, Colorectal, and Cervical Screening Cancer Tests among Hispanic Patients. Int J Environ Res Public Health 13:ijerph13010021
Zueva, Lidia; Golubeva, Tatiana; Korneeva, Elena et al. (2016) Foveolar Müller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency. Microsc Microanal 22:379-86

Showing the most recent 10 out of 104 publications