Despite a greater accumulation of risk factors for at-risk drinking and alcohol use disorders, national epidemiological surveys consistently report that Blacks and Hispanics in the United States (US) have an comparable or lower prevalence of binge drinking and alcohol disorders compared to non-Hispanic Whites. However, mortality data indicate that they have higher rates of alcohol-attributable motor vehicle crash fatality (MVCF). These seemingly divergent patterns indicate an epidemiologic paradox, the consequences of which are important for public health: MVCF is a leading cause of death among young adults, Blacks and Hispanics experience substantial inequities in MVCF compared to non-Hispanic Whites, and approximately 30% of all MVCFs are alcohol-related. In the present application for a Mentored Research Scientist Development Award (K01), I propose to develop expertise in four areas that will allow me to develop a line of research into the racial/ethnic paradox in alcohol-related health: 1) Built environment effects on alcohol-related health;2) Conceptualization and measurement of cultural and social norms regarding alcohol use;3) Analysis of repeated measures data;and 4) Field methods in epidemiologic data collection. I will use the skills obtained in these training areas to begin to fill outstanding gaps in our understanding of racial/ethnic differences in alcohol- related health with three research projects, for which the K01 will allow me protected research time that would otherwise not be possible as a new assistant professor. First, I will probe the validity of the racial/ethnic paradox itself. I ill explore whether lower rates of problem drinking among racial/ethnic minorities are limited to adolescents and young adults, and whether rates of problem drinking among older adults are higher among Blacks and Hispanics compared to non-Hispanic Whites. This work will utilize a national longitudinal dataset and incorporate information on trajectories within Blacks and Latino subgroups, which have never been characterized. Second, I will determine if alcohol-related social norms mediate overall differences in alcohol use and MVC risk, adding to our knowledge of how the paradox arises. I will use data from the New York Social Environment Survey, an epidemiologic study in New York City with rich racial and ethnic diversity and one of the only community-based samples to measure alcohol norms. Third, I will test a potential mechanism to explain the racial/ethnic paradox: that Black and Hispanic individuals experience more alcohol-attributable MVCF because the built environment in which they consume alcohol is more dangerous (e.g., worse road conditions). To test this hypothesis I propose a novel study linking records from the Fatality Analysis Reporting System on a national level with census and land usage information. In addition to these research aims, my K01 award period will focus on preparation of an R01 grant proposal to collect original data on racial/ethnic differences in alcohol-related health that builds on and extends the research proposed here. These projects are feasible only if I have protected time for new training and research, which K01 funding will provide.

Public Health Relevance

The present proposal examines a long-standing but little investigated 'paradox'in alcohol epidemiology: epidemiological surveys consistently report that Black and Latino populations have comparable or lower prevalence of alcohol disorders compared to non-Hispanic Whites, but bear a disproportionate amount of harm from alcohol in the form of injury and illness. The training and research proposed here will form the background of a new line of inquiry to examine how racial/ethnic differences are shaped over the life course, and how the built environment as well as cultural/social norms shape alcohol-related risk. These inquires have substantial promise for public health;accurate empirical data regarding the emergence of racial/ethnic differences across the life course and explanations for the epidemiologic 'paradox'in alcohol-related health are crucial to better understanding the role of minority status in the development and persistence of alcohol disorders as well as alcohol-related motor-vehicle crash risk.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
1K01AA021511-01A1
Application #
8510260
Study Section
Health Services Research Review Subcommittee (AA)
Program Officer
Godette, Dionne
Project Start
2013-06-23
Project End
2018-05-31
Budget Start
2013-06-23
Budget End
2014-05-31
Support Year
1
Fiscal Year
2013
Total Cost
$182,902
Indirect Cost
$12,932
Name
Columbia University (N.Y.)
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
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Martins, Silvia S; Kim, June H; Chen, Lian-Yu et al. (2015) Nonmedical prescription drug use among US young adults by educational attainment. Soc Psychiatry Psychiatr Epidemiol 50:713-24
Keyes, Katherine M; Cerda, Magdalena; Brady, Joanne E et al. (2014) Understanding the rural-urban differences in nonmedical prescription opioid use and abuse in the United States. Am J Public Health 104:e52-9
Keyes, Katherine M; Susser, Ezra (2014) The expanding scope of psychiatric epidemiology in the 21st century. Soc Psychiatry Psychiatr Epidemiol 49:1521-4
Welch, Alice E; Caramanica, Kimberly; Maslow, Carey B et al. (2014) Frequent binge drinking five to six years after exposure to 9/11: findings from the World Trade Center Health Registry. Drug Alcohol Depend 140:1-7
Keyes, Katherine M; Pratt, Charissa; Galea, Sandro et al. (2014) The burden of loss: unexpected death of a loved one and psychiatric disorders across the life course in a national study. Am J Psychiatry 171:864-71
Keyes, Katherine M; Shmulewitz, Dvora; Greenstein, Eliana et al. (2014) Exposure to the Lebanon War of 2006 and effects on alcohol use disorders: the moderating role of childhood maltreatment. Drug Alcohol Depend 134:296-303
Keyes, Katherine M; Nicholson, Ryan; Kinley, Jolene et al. (2014) Age, period, and cohort effects in psychological distress in the United States and Canada. Am J Epidemiol 179:1216-27
Keyes, Katherine M; Cheslack-Postava, Keely; Westhoff, Carolyn et al. (2013) Association of hormonal contraceptive use with reduced levels of depressive symptoms: a national study of sexually active women in the United States. Am J Epidemiol 178:1378-88