Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01DK063051-02
Application #
6706402
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
2003-02-15
Project End
2005-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$88,557
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Garcia-Roves, Pablo; Huss, Janice M; Han, Dong-Ho et al. (2007) Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. Proc Natl Acad Sci U S A 104:10709-13
Huss, Janice M; Imahashi, Ken-ichi; Dufour, Catherine R et al. (2007) The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload. Cell Metab 6:25-37
Dufour, Catherine R; Wilson, Brian J; Huss, Janice M et al. (2007) Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab 5:345-56
Garcia-Roves, Pablo M; Huss, Janice; Holloszy, John O (2006) Role of calcineurin in exercise-induced mitochondrial biogenesis. Am J Physiol Endocrinol Metab 290:E1172-9
Huss, Janice M; Kelly, Daniel P (2005) Mitochondrial energy metabolism in heart failure: a question of balance. J Clin Invest 115:547-55
Huss, Janice M; Kelly, Daniel P (2004) Nuclear receptor signaling and cardiac energetics. Circ Res 95:568-78
Huss, Janice M; Torra, Ines Pineda; Staels, Bart et al. (2004) Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Mol Cell Biol 24:9079-91